Formulari Ubat KKM (FUKKM)

# Generic Name MDC Category Indications Pres. Restrictions Dosage
181 Betamethasone Sodium Phosphate 4 mg/ml Injection H02AB01162P3001XX B Pre-operative and in serious trauma or illness, shock, as adjunctive therapy in rheumatoid disorders, ocular, dermatologic and respiratory allergic and inflammatory states Usual intravenous doses are up to 9 mg/day of the sodium phosphate salt only. CHILD: IM: 0.5 - 7.7 mg base/m2/day divided every 6 - 12 hours. ADOLESCENT and ADULT, IM: 0.6 - 9 mg divided every 12 - 24 hours
182 Bicalutamide 50 mg Tablet L02BB03000T1001XX A* Androgen deprivation therapy in advanced prostate cancer in combination with luteinising hormone-releasing hormone (LHRH) analogue therapy or surgical castration. 50 mg once daily. (morning or evening), with or without food. Take on the same time each day. Adult: When used with gonadorelin analogue: Usual dose: 50 mg once daily. May be started with or at least 3 days before starting gonadorelin analogue therapy.
183 Bimatoprost 0.01% ophthalmic solution S01EE03000D20-02XXX A* Reduction of elevated intraocular pressure in chronic open-angle glaucoma and ocular hypertension in adults (as monotherapy or as adjunctive therapy to beta blockers). To be used as 2nd line One drop in the affected eye(s) once daily, administered in the evening.
184 Bisacodyl 10 mg Suppository A06AB02000S2002XX C i) Constipation ii) Bowel preparation for radiological procedures and surgery i) ADULT and CHILD over 10 years: 10 mg, CHILD less than 10 years 5 mg insert rectally ii) ADULT 10-20 mg, CHILD over 4 years 5 mg the following morning before procedures insert rectally
185 Bisacodyl 5 mg Suppository A06AB02000S2001XX C i) Constipation ii) Bowel preparation for radiological procedures and surgery i) ADULT and CHILD over 10 years: 10 mg, CHILD less than 10 years 5 mg insert rectally ii) ADULT 10-20 mg, CHILD over 4 years 5 mg the following morning before procedures insert rectally
186 Bisacodyl 5 mg Tablet A06AB02000T1001XX C i) Constipation ii) Bowel preparation for radiological procedures and surgery i) ADULT and CHILD over 10 years 5-10 mg, CHILD 4-10 years 5 mg. To be taken at night for effect on the following morning ii) ADULT 10-20 mg the night before procedures, CHILD over 4 years 5 mg the night before procedures
187 Bismuth Subnitrate, Iodoform and Liquid Paraffin Paste R01AX30984G6001XX B As a mild antiseptic for wounds and abscesses. Sterile gauze impregnated with paste for packing cavities after otorhinological surgery As directed for local application
188 Bisoprolol Fumarate 2.5 mg Tablet C07AB07-000-T10-01-XXX B i) Hypertension ii)Coronary heart disease (angina pectoris) iii) Treatment of stable congestive cardiac failure in addition to ACEI's and diuretics 1.25 mg once daily, gradually titrate to maximum tolerable dose (i) & (ii): Max: 20mg/ day (iii): Max 10mg/ day
189 Bisoprolol Fumarate 5 mg Tablet C07AB07-000-T10-02-XXX B i) Hypertension ii)Coronary heart disease (angina pectoris) iii) Treatment of stable congestive cardiac failure in addition to ACEI's and diuretics 1.25 mg once daily, gradually titrate to maximum tolerable dose (i) & (ii): Max: 20mg/ day (iii): Max 10mg/ day
190 Bleomycin 15 mg Injection L01DC01110P4001XX A Solid tumours; Lymphomas 15 - 30 mg weekly in divided doses or 10 - 20 mg/m2 once or twice weekly or 10 mg/m2 slow bolus in 15 minutes D1 and D15. Total dosage:should not exceed 300 mg. CHILD: 10 - 15 mg/m2 over 6 hours every 3 - 4 weeks (Routes: SC, IM, IV (either as bolus or as infusion over 24 hours), intra-arterial, intra-pleural)
191 Bortezomib 3.5 mg Injection L01XX32000P3001XX A* Treatment of multiple myeloma 1.3 mg/m2 bodysurfacearea twice weekly for two weekson days 1, 4, 8, and 11 in a 21-day treatment cycle. At least 3 days should elapse between consecutive doses of bortezomib.
192 Bosentan 125 mg tablet C02KX01-000-T10-01-XXX A* Treatment of pulmonary arterial hypertension (PAH) in patients of WHO functional class II-IV. - Initially 62.5 mg bd for 4 weeks, then increase to the maintenance dose of 125 mg bd
193 Brimonidine Tartrate 0.15% Ophthalmic S01EA05123D2001XX A* Lowering of intraocular pressure in patients with open-angle glaucoma or ocular hypertension 1 drop in the affected eye(s) 3 times daily
194 Brinzolamide 1% and Brimonidine tartrate 0.2% ophthalmic suspension S01EC54-990-D20-01-XXX A* Decrease of elevated intraocular pressure (IOP) in adult patients with open-angle glaucoma or ocular hypertension for whom monotherapy provides insufficient IOP reduction. 1 drop in the affected eye(s) 2 times daily.
195 Brinzolamide 1% ophthalmic suspension S01EC04-000-D20-01-XXX A* Indicated for the treatment of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. For patients who require carbonic anhydrase inhibitor (CAI) but could not tolerate Dorzolamide. 1 drop 2 times daily. Some patients may have a better response with one drop three times a day. The dose should not exceed 1 drop in the affected eye(s) 3 times daily.
196 Bromazepam 3 mg Tablet N05BA08000T1002XX A Anxiety disorders Adult: Initially, 6-18 mg daily in divided doses. Doses up to 60 mg daily have been used. Elderly: Max initial dose: 3 mg daily
197 Bromhexine HCl 4 mg/2 ml Injection R05CB02110P3001XX A Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucous secretion and impaired mucous transport - 4mg SC, IM or IV 2 - 3 times daily (maximum 12mg/day).
198 Bromhexine HCl 4 mg/5 ml Oral Solution R05CB02110L1001XX B Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucous secretion and impaired mucous transport - Adult: 8-16 mg three times daily. Children: By body weight: 0.3 mg/kg/day 8 hourly for 7 days, then 0.15 mg/kg/day 8 hourly; or Based on age: 6-12 years – 4mg three times daily; 2-6 years – 2mg three times daily; Less than 2 years – 1mg three times daily.
199 Bromhexine HCl 8 mg Tablet R05CB02110T1001XX C Secretolytic therapy in acute and chronic bronchopulmonary diseases associated with abnormal mucous secretion and impaired mucous transport. Medical Assistant in health settings without Medical Officer is allowed to prescribe this medicine for adult use only. Adult: 8-16 mg three times daily. Children: By body weight: 0.3 mg/kg/day 8 hourly for 7 days, then 0.15 mg/kg/day 8 hourly; or Based on age: 6-12 years – 4 mg three times daily; 2-6 years – 2 mg three times daily
200 Bromocriptine Mesilate 2.5 mg Tablet G02CB01196T1001XX A/KK i) Hypogonadism or Galactorrhoea ii) Acromegaly i) Initially 1 - 1.25 mg at bedtime increased gradually, usual dose: 7.5 mg daily in divided doses. Max 30 mg daily ii) 1.25 - 2.5 mg at bedtime for 3 days and may be increased by 1.25 - 2.5 mg every 3 - 7 days up to 30 mg a day in divided doses
201 Budesonide 1 mg/2 ml Nebuliser Solution R03BA02000A3002XX B Maintenance treatment of asthma as prophylactic therapy especially if not fully controlled by bronchodilators ADULT : Initially 1 - 2 mg twice daily. CHILD 3 months - 12 years of age : 500 mcg - 1 mg. Maintenance dose : half of the above doses
202 Budesonide 100 mcg/dose Inhaler R03BA02000A2101XX B Maintenance treatment of asthma as prophylactic therapy especially if not fully controlled by bronchodilators ADULT:200 - 1600 mcg daily in 2-4 divided doses. Maintenance with twice daily dosing. CHILD more than 7 years: 200-800 mcg, 2 - 7 years: 200-400 mcg. To be inhaled in 2 - 4 divided doses.
203 Budesonide 160 mcg and Formoterol 4.5 mcg Inhalation R03AKO7-989-A21-01-XXX A/KK Category of prescriber A/KK: i) Regular treatment of asthma where use of a combination (inhaled corticosteroid and long-acting beta2-agonist) is appropriate: - Patients not adequately controlled with inhaled corticosteroids and "as needed" inhaled short-acting beta2-agonists. or - Patients already adequately controlled on both inhaled corticosteroids and long- acting beta2-agonists. ii) As a reliever treatment for mild asthma patients who do not adhere to regular inhaled corticosteroid Category of prescriber A*: iii) Treatment of COPD patients with a blood eosinophil count of 300 cells/microliter and more iv) Treatment of COPD patients with blood eosinophil count of 100 cells/microliter and more with history of repeated exacerbation despite regular treatment with long-acting bronchodilators. - i) Asthma Maintenance therapy: Adult ≥18 yr 160 mcg to 320 mcg bd. Some patients may require up to a max of 640 mcg bd. Adolescent 12-17 yr 160 mcg to 320 mcg bd. Childn 6-11 yr 160 mcg bd, <6 yr Not recommended. Maintenance & relief Adult and adolescent ≥12 yr 320 mcg/day either as 160 mcg bd or 320 mcg od either morning or evening. For some patients a maintenance dose of 320 mcg bd may be appropriate. Patients should take 160 mcg additional inhalation as needed in response to symptoms. If symptoms persist after a few minutes, an additional inhalation should be taken. Not more than 960 mcg should be taken on any single occasion. A total daily dose of more than 1280 mcg is not normally needed, however a total daily dose of up to 1920 mcg could be used for a limited period. Patients using more than 1280 mcg daily should seek medical advice, should be reassessed & their maintenance therapy reconsidered. ii) Asthma reliever-only therapy: 160 mcg as needed, but no more than 960 mcg to be taken on any single occasion. Children <12 yr: Not recommended iii & iv) COPD: Adult ≥18 yr 320 mcg bd.
204 Budesonide 200 mcg/dose Inhalation R03BA02000A2102XX B Maintenance treatment of asthma as prophylactic therapy especially if not fully controlled by bronchodilators ADULT: 200-1600 mcg daily in 2-4 divided doses. Maintenance with twice daily dosing. CHILD more than 7 years: 200-800 mcg, 2 - 7 years: 200-400 mcg. To be inhaled in 2-4 divided doses.
205 Budesonide 500 mcg/2 ml Nebuliser Solution R03BA02000A3001XX B Maintenance treatment of asthma as prophylactic therapy especially if not fully controlled by bronchodilators ADULT : Initially 1 - 2 mg twice daily. CHILD 3 months - 12 years of age : 500 mcg - 1 mg. Maintenance dose : half of the above doses
206 Budesonide 64mcg Nasal Spray R01AD05000A4103XX A/KK Seasonal allergic, perennial rhinitis and nasal polyposis ADULT and CHILD 6 years and older. Rhinitis : 2 spray into each nostril once daily in the morning or 1 spray into each nostril twice daily. Nasal polyps : 2 spray twice daily
207 Bumetanide 0.5 mg/ml Injection C03CA02000P3001XX A* Oedema used in furosemide allergic patient IV injection: 1 - 2 mg repeated after 20 mins. IV infusion: 2 - 5 mg over 30 - 60 mins
208 Bumetanide 1 mg Tablet C03CA02000T1001XX A* Oedema used in furosemide allergic patient 1 mg in the early evening. Up to 5 mg daily in severe cases
209 Bupivacaine 0.5 % Heavy Injection N01BB01110P3003XX A Used for spinal anaesthesia ADULT: 2 - 4 ml. Not to exceed 2 mg/kg in a single dose
210 Bupivacaine 0.5 % Injection N01BB01110P3002XX B For peripheral sympathetic nerve and epidural (excluding caudal) anaesthesia and obstetrics anaesthesia Regional nerve block or epidural block: 15 - 30 ml. Nerve block of finger or toe: 2 - 6 ml. Maximum: 2 mg/kg body weight in any 4 hours period, equivalent to 25 - 30 ml in adults of average weight

Halaman-halaman