Formulari Ubat KKM (FUKKM)

# Generic Name MDC Category Indications Dosage
301 Cetrorelix 0.25 mg Injection H01CC02122P4001XX A* Prevention of premature ovulation in patients undergoing a controlled ovarian stimulation, followed by oocyte pick-up and assisted reproductive techniques Given by SC 0.25 mg/day, given either in the morning beginning on the day 5 or 6 of ovarian stimulation or in the evening beginning on day 5, and continued until ovulation induction
302 Cetuximab 5 mg/ml Solution for Infusion L01XC06000P5002XX A* For neo-adjuvant treatment of KRAS wild type metastatic colorectal cancer with the aim of liver resection with the following conditions: i) The primary colorectal tumour has been resected or is potentially resected. ii)The metastatic disease is confined to the liver and is unresectable iii) The patient is fit enough to undergo surgery to resect the primary colorectal tumour and to undergo liver surgery if the metastases become resectable after treatment with cetuximab. iv)The treatment is limited to 16 weeks Administered once a week. The very first dose is 400mg cetuximab per m2 body surface area with a recommended infusion period of 120 minutes. All subsequent weekly doses are 250mg per m2 body surface area each with a recommended infusion period of 60 minutes. The maximum infusion rate must not exceed 10mg/min.
303 Charcoal, Activated 250 mg Tablet A07BA01000T1001XX C i) Diarrhoea and food poisoning ii) Reduce absorption of drugs, plant, inorganic poison and chemicals in poisoning cases i) ADULT 0.5-1 g given 3-4 times daily. CHILD half adult dose. ii) Need to be dissolved in liquid (slurry consistency). ADULT and CHILD over 12 years: initial 30-100 g or 1-2 g/kg; repeat initial dose as soon as possible or 20-50 g every 2-6 hours. CHILD over 1-12 years, 25-50 g or 1-2 g/kg; may repeat half the initial dose every 2-6 hour as needed. CHILD to 1 year of age, 1 g/kg; may repeat half the initial dose every 2-6 hours as needed. For maximum efficacy administer within 1 hour after ingestion of toxic compound
304 Charcoal, Activated 50 g Granules A07BA01000F1001XX A Emergency treatment of acute oral poisoning and drug overdose ADULT:Acute poisoning: 50 - 100g in suspension. Severe poisoning: 50 - 100g as an initial dose followed by 20g every 4 - 6 hours. CHILDREN: 1g/kg/dose
305 Chloral Hydrate 200 mg/5 ml Mixture N05CC01010L2101XX B Preoperative sedation ADULT : 0.5 - 1 g (max 2 g) with plenty of water at bedtime. CHILD : Neonate: 30-50 mg/kg; up to 100 mg/kg may be used with respiratory monitoring. 1 mth-12 yr: 30-50 mg/kg (max: 1 g); up to 100 mg/kg (max: 2 g) may be used; 12-18 yr: 1-2 g. Doses to be taken 45-60 minutes before procedure. May be given rectally if oral route is not available.
306 Chlorambucil 2 mg Tablet L01AA02000T1001XX A Low grade lymphoma, chronic lymphocytic leukaemia. Ovarian cancer General : Initial :0.1 -0.2 mg/kg body weight daily for 4 - 8 weeks maintanance : given either by reduced daily dosage or intermittent course of treatment. Chronic Lymphocytic Leukaemia: initial : 0.15mg/kg/day untill total leukocyte count has fallen to 10,000peruL, then resumed treatment untill 4 weeks after the end of the first course then continued at a dosage 0.1mg/kg/day.
307 Chloramphenicol 0.5% Eye Drops S01AA01000D2001XX C Broad spectrum antibiotic in superficial eye infections Instill 1 drop of a 0.5% solution every 2 hr. Increase dosage interval upon improvement. To continue treatment for at least 48 hr after complete healing
308 Chloramphenicol 1% Eye Ointment S01AA01000G5101XX C Treatment of ocular infections involving the conjunctiva and/or cornea caused by chloramphenicol susceptible organisms ADULT and CHILD : Apply to the conjunctiva, a thin strip (approximately 1 cm) of ointment every 3 hours or more frequently
309 Chloramphenicol 250 mg Capsule J01BA01126C1001XX B Treatment of typhoid, paratyphoid fevers, bronchopneumonia and enteric infection ADULT: 500 mg 4 times daily or 50 mg/kg/day in 4 divided doses. Maximum dose: 4 g/day. CHILD: 25 - 100 mg/kg/day in 4 divided doses
310 Chloramphenicol 5% w/v Ear Drops S02AA01000D1001XX C Acute otitis media, otitis externa with perforation Apply 2 - 3 drops into the ear 2 - 3 times daily. Not to be used for long term
311 Chloramphenicol Sodium Succinate 1 g Injection J01BA01520P4001XX B Treatment of typhoid, paratyphoid fevers, bronchopneumonia and enteric infection Adult:50 to 100 mg/kg/day in 4 divided doses. Premature and full-term neonates: 25 mg/kg/day in 4 divided doses. Full-term infants >2 wk: 50 mg/kg/day in 4 divided doses. Children: 50-100 mg/kg/day in 4 divided doses
312 Chlorhexidine 1:200 in Alcohol with Emollient (Hand Disinfectant). D08AC52137L9901XX C+ To be used undiluted for hand and skin disinfections Pre-op surgical hand disinfection: Spread 5ml throughly over both hands and forearms, rubbing vigorously. When dry apply a further 5ml and repeat procedure. Antiseptic hand disinfection on the ward: Spread 3ml throughly over the hands and wrist rubbing vigorously until dry. Disinfection of patient's skin: Prior to surgery, apply to a sterile swab and rub thoroughly over the operation site for a minimum of 2 mins
313 Chlorhexidine Gluconate 0.2 % Mouthwash R02AA05137M2001XX C As a gargle Rinse mouth with 10 ml for about 1 minute twice daily
314 Chlorhexidine gluconate 1% cream D08AC02137G1001XX C+ As a disinfectant cream. It can be used for disinfection or lubricating during gynaecological and obstetric procedures or childbirth. Clean the affected skin area and apply cream as required.
315 Chlorhexidine Gluconate 2% in Alcohol 70% Solution D08AC52137L9902XX C Use as disinfectant in central venous catheter care bundle Skin Preparation: Use Chlorhexidine Gluconate 2% in Isopropyl Alcohol 70% and allow to dry. Catheter access: Apply to catheter ports or hubs prior to accessing the line for administering fluids or injections
316 Chlorhexidine Gluconate 4% Scrub D08AC02137M9901XX C+ Surgical hand scrub/disinfection, pre-op skin preparation Surgical hand disinfection: Apply 5ml to clean hands and forearms for 1 min. Rinse and repeat with another 5ml for a further 2 mins and then rinse and dry. General skin disinfection: Apply appropriate quantity to wet area and scrub for 1 min. Rinse thoroughly & dry
317 Chlorhexidine Gluconate 5% Solution D08AC02137L9901XX C+ i) Preoperative skin disinfection ii) Wounds or burns iii) Emergency disinfection of instruments i) & iii) 1 : 10 in 70 % Alcohol ii) 1 : 100
318 Chlorinated Lime Powder V07AV00000F9901XX C Antiseptic and disinfectants Not applicable
319 Chlorinated Lime Solution & Buffered Acetate Solution D08A000999G9901XX C Wound or ulcer Apply to affected areas undiluted as a cleansing agent
320 Chloroquine Phosphate 250 mg Tablet (150 mg Chloroquine base) P01BA01162T1001XX C Treatment of malaria - acute attack ADULT 600 mg base stat, 300 mg 6 - 8 hours later and a further 300 mg on each of 2 following days. CHILD 3 - 4 years : 150 mg base stat, 75 mg 6 hours later, then 75 mg daily for 2 days. CHILD 5 - 8 years : 300 mg stat, 150 mg 6 hours later, then 150 mg daily for 2 days
321 Chlorpheniramine Maleate 10 mg/ml Injection R06AB04253P3001XX B Allergic conditions 10 - 20 mg IM or SC, repeated if required. Not to exceed 40 mg in 24 hours. 10 - 20 mg over 1 minute by slow IV
322 Chlorpheniramine Maleate 2 mg/5 ml Syrup R06AB04253L9001XX C Symptomatic treatment of allergic conditions responsive to antihistamine CHILD 2 - 5 years : 1 mg every 4 - 6 hours (maximum 6 mg daily) 6 - 12 years : 2 mg every 4 - 6 hours (maximum 12 mg daily)
323 Chlorpheniramine Maleate 4 mg Tablet R06AB04253T1001XX C Symptomatic treatment of allergic conditions responsive to antihistamines ADULT : 4 mg every 4 - 6 hours. Maximum 24 mg daily. CHILD 2 - 5 years : 1 mg every 4 - 6 hours (maximum 6 mg daily) 6 - 12 years : 2 mg every 4 - 6 hours (maximum 12 mg daily)
324 Chlorpromazine HCl 100 mg Tablet N05AA01110T1002XX B Psychosis mania and agitation ADULT : Initial dose - 25 mg 3 times daily according to response up to 1 g daily. PAEDIATRIC: Up to 5 years: 0.5 mg/kg body weight every 4 - 6 hours (Maximum 40 mg daily). CHILD 6 - 12 years: A third to half adult dose (Maximum 75 mg daily)
325 Chlorpromazine HCl 25 mg Tablet N05AA01110T1001XX B Psychosis mania and agitation ADULT : Initial dose - 25 mg 3 times daily according to response up to 1 g daily. PAEDIATRIC: Up to 5 years: 0.5 mg/kg body weight every 4 - 6 hours (Maximum 40 mg daily). CHILD 6 - 12 years: A third to half adult dose (Maximum 75 mg daily)
326 Chlortetracycline 1% Eye Ointment S01AA02000G5101XX B Eye infections requiring a broad spectrum antibiotic Apply thin strip (approximately 1 cm) to the conjuctiva 2 to 4 hourly or more frequently.
327 Chlortetracycline 1-3 % Cream D06AA02000G1001XX B Bacterial skin infections Apply directly to affected area twice daily as required for 1 - 2 weeks
328 Cholera Vaccine J07AE01000P3001XX B Immunisation of cholera Prophylactic ADULT: First dose of 0.5 ml SC/IM followed after 1 - 4 weeks by a second dose of 1 ml. CHILD: 1 - 5 years: 0.1 ml (1st dose), 0.3 ml (2nd dose). CHILD; 5 - 10 years: 0.3 ml (1st dose), 0.5ml (2nd dose). Booster: For optimum long-term protection, a booster dose is recommended for adults after 2 years. Children 2-6 years should receive a booster dose after 6 months.
329 Cholestyramine Resin 4 G C10AC01000M4001XX A i) Hypercholesterolemia ii) Familial hypercholesterolemia - heterozygous iii) Generalized atherosclerosis iv) Diarrhoea due to bile acid malabsorption v) Pruritus of skin associated with partial biliary obstruction Hypercholesterolemia: Adjunct: initial, 4 g orally 1-2 times daily, maintenance, 8 to 16 g in divided doses, max 24 g daily CHILD: 50 - 150 mg/ kg 6 - 8 hourly oral
330 Choline Salicylate 8.7%, Cetylkonium Chloride 0.01% Dental Gel N02BA03900G3001XX B For relief of the pain and discomfort in mouth ulcers and sores, infant teething and denture irritation Apply to area 4 times daily

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